PUBLICATIONS

Fanczal J, Pallagi P, Görög M, Diszházi G, Almássy J, Madácsy T, Varga Á, Csernay-Biró P, Katona X, Tóth E, Molnár R, Rakonczay Z Jr, Hegyi P, Maléth J. TRPM2-mediated extracellular Ca2+ entry promotes acinar cell necrosis in biliary acute pancreatitis. J Physiol. 2020 Mar;598(6):1253-1270.

Molnár R, Madácsy T, Varga Á, Németh M, Katona X, Görög M, Molnár B, Fanczal J, Rakonczay Z Jr, Hegyi P, Pallagi P, Maléth J. Mouse pancreatic ductal organoid culture as a relevant model to study exocrine pancreatic ion secretion. Lab Invest. 2020 Jan;100(1):84-97.

Maléth J, Choi S, Muallem S, Ahuja M. Translocation Between PI(4,5)P2-Poor and PI(4,5)P2-Rich Microdomains During Store Depletion Determines STIM1 Conformation and Orai1 Gating. Nature Communications 2014 Dec 17;5:5843.

Maléth J, Balla Z, Kui B, Balázs A, Katona M, Judák L, Németh I, Pallagi P, Kemény LV, Rakonczay Jr. Z, Venglovecz V, Földesi I, Pető Z, Somorácz Á, Borka K, Perdomo D, Lukacs GL, Gray MA, Monterisi S, Zaccolo M, Sendler M, Mayerle J, Kühn JP, Lerch MM, Sahin-Tóth M, Hegyi P. Alcohol Disrupts Levels and Function of the Cystic Fibrosis Transmembrane Conductance Regulator to Promote Development of Pancreatitis. Gastroenterology 2015 Feb;148(2):427-39.e16.

Jha A, Ahuja M, Maléth J, Moreno CM, Yuan JP, Kim MS, Muallem S. The STIM1 CTID domain determines access of SARAF to SOAR to regulate Orai1 channel function. J Cell Biol. 2013 8;202(1):71-9.

Pallagi P, Venglovecz V, Rakonczay Z Jr, Borka K, Korompay A, Ózsvári B, Judák L, Sahin-Tóth M, Geisz A, Schnúr A, Maléth J, Takács T, Gray MA, Argent BE, Mayerle J, Lerch MM, Wittman T, Hegyi P. Trypsin reduces pancreatic ductal bicarbonate secretion by inhibiting CFTR Cl− channels and luminal anion exchangers. Gastroenterology 2011;141, 2228–2239.e6.

Maléth J, Venglovecz V, Rázga Zs, Tiszlavicz L, Rakonczay Z, Hegyi P. The non-conjugated chenodeoxycholate induces severe mitochondrial damage and inhibits bicarbonate transport in pancreatic duct cells. Gut 2011; 60(1):136-8.

Nekkaa I, Bogdán D, Gáti T, Béni S, Juhász T, Palkó M, Paragi G, Tóth G K, Fülöp F, Mándity I M. Flow-chemistry enabled efficient synthesis of β-peptides: backbone topology vs. helix formation Chemical Communications 2019;  3061-3064.

Orsy G, Fülöp F, Mándity I M. Continuous-flow catalytic deuterodehalogenation carried out in propylene carbonate Green Chemistry 2019; 21(5)  956-961.

Mándity I M, Monsignori A, Fülöp L, Forrõ E, Fülöp F. Exploiting aromatic interactions for β-peptide foldamer helix stabilization: A significant design element Chemistry- A European Journal 2014; 20, 4591-4597.

 

Mándity I M, Olasz B, Ötvös S B, Fülöp F. Continuous-flow solid-phase peptide synthesis: a revolutionary reduction of the amino acid excess CHEMSUSCHEM 2014; 7(11) 3172-3176.

Ötvös S B, Mándity I M, Fülöp F. Highly Efficient 1,4-Addition of Aldehydes to Nitroolefins: Organocatalysis in Continuous Flow by Solid-Supported Peptidic Catalysts CHEMSUSCHEM  2012; 5(2) 266-269.

Mándity I M, Fülöp L, Vass E, Tóth G K, Martinek TA, Fülöp F. Building beta-Peptide H10/12 Foldamer Helices with Six-Membered Cyclic Side-Chains: Fine-Tuning of Folding and Self-Assembly Organic Letters 2010 12(23) 5584-5587.

Mándity I M, Weber E, Martinek TA, Olajos G, Toth GK, Vass E, Fülöp F. Design of Peptidic Foldamer Helices: A Stereochemical Patterning Approach Angew. Chem. Int. Ed. 2009; 48 (12) 2171-2175.

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